Table 3.
Core metazoan metzincins and deuterostome innovations.
| Gene family | Ancestral protostome* | Ciona | Human | Zebrafish | |
| ADAM | 3 | 3 | 21 | 22 | |
| ADAMTS | 5 | 7 | 25 | 27 | |
| BMP1/TLL | 1 | 1 | 3 | 4 | |
| Meprin | 0 | 0 | 2 | 4 | |
| MMP | 2 | 5 | 25 | 26 | |
| TIMP | 1 | 1 | 4 | 4 |
The number of genes present in the ancestral protostomes and chordate lineages are displayed for their respective gene family. * Ancestral Protostome content is the representative gene content based on Drosophila melanogaster, Apis mellifera, Anopheles gambiae and Caenorhabditis elegans genomes.