Table 1.
Characteristics of participants in women's health study cognitive cohort at randomisation. Values are numbers (percentages) unless stated otherwise
| Characteristics | Aspirin group (n=3215) | Placebo group (n=3162) | P value |
|---|---|---|---|
| Mean (SD) age (years) at randomisation | 66.2 (4.1) | 66.3 (4.1) | 0.21 |
| Mean (SD) age (years) at initial cognitive assessment | 71.8 (4.1) | 71.9 (4.1) | 0.19 |
| Self reported perceived change in memory in past year*: | |||
| None or improved | 83.0 | 82.8 | 0.84 |
| Memory worse | 17.0 | 17.2 | |
| Highest attained education: | |||
| LPVN, associates degree, registered nurse | 66.6 | 67.7 | 0.37 |
| Bachelors degree, masters degree, doctorate | 33.4 | 32.3 | |
| Cigarette smoking: | |||
| Never | 53.3 (1712) | 51.6 (1629) | 0.30 |
| Former | 37.1 (1192) | 38.0 (1203) | |
| Current | 9.6 (307) | 10.4 (328) | |
| Alcohol consumption: | |||
| Less than weekly | 59.4 (1909) | 59.3 (1874) | 0.95 |
| Weekly | 28.5 (916) | 28.4 (896) | |
| Daily | 12.1 (389) | 12.3 (389) | |
| Body mass index: | |||
| <25 | 49.4 (1549) | 50.9 (1574) | 0.49 |
| 25-9 | 35.1 (1100) | 34.2 (1058) | |
| ≥30 | 15.5 (486) | 14.9 (460) | |
| Physical exercise: | |||
| Less than once weekly | 59.7 (1919) | 59.3 (1873) | 0.70 |
| Once or more weekly | 40.3 (1293) | 40.7 (1287) | |
| Hormone replacement therapy use: | |||
| Never | 40.0 (1285) | 40.0 (1261) | 0.67 |
| Past | 19.1 (613) | 19.9 (628) | |
| Current | 40.9 (1314) | 40.1 (1266) | |
| Medical history: | |||
| Diabetes mellitus | 3.4 (110) | 3.5 (111) | 0.85 |
| Hypertension | 40.9 (1315) | 39.2 (1240) | 0.18 |
| Hyperlipidaemia | 42.5 (1365) | 43.5 (1374) | 0.42 |
| Depression‡ | 6.0 (191) | 5.8 (181) | 0.69 |
LPVN=licensed practical or vocational nurse.
*At run-in period.
‡Assessed four years after randomisation.