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. 2007 May 3;6:54. doi: 10.1186/1475-2875-6-54

Table 3.

Frequency of dhfr and dhps mutant alleles, genotypic study, Lainé refugee camp

Genotype Frequencies n % 95% CI
dhps (N = 114)
wild type, 8 7.0 3.1–13.6
single mutant 436 31 27.2 19.3–36.3
single mutant 437 38 33.3 24.8–42.8
double mutant 436–437 29 25.4 17.7–34.4
double mutant 437–540 8 7.0 3.1–13.6
dhfr (N = 148)
wildtype 20 13.5 8.4–20.1
double mutant 59–108 2 1.4 0.2–4.8
triple mutant 51–59–108 126 85.1 78.4–90.4
dhps and dhfr combined (N = 110)
quintuple mutant: dhfr 51–59–108 &dhps 437–540 8 7.3 3.2–13.8
quintuple mutant: dhfr 51–59–108 & dhps 436–437 27 24.5 16.8–33.7
dhfr 51–59–108 & dhps single mutant 54 49.1 39.4–58.8
Three or less mutations 21 19.1 12.2–27.7

Dhfr: dihydrofolate reductase

Dhps: dihydropterase synthetase