Table 2.
A Qualitative Analysis of the Immunohistochemical Data from Spinal Cord (SC) and Motor Cortex (MC) Tissues
| Cases | Cyclin D1 | CDK4 | ppRb | E2F-1 | ||||
|---|---|---|---|---|---|---|---|---|
| SC | MC | SC | MC | SC | MC | SC | MC | |
| C 1 | ND | Low | Low | Low | ND | Low | ND | ND |
| C 2 | ND | ND | ND | ND | Low | ND | ND | ND |
| C 3 | ND | Low | ND | ND | ND | ND | ND | ND |
| C 8 | ND | ND | ND | ND | ND | ND | ND | ND |
| C 9 | ND | ND | ND | ND | ND | ND | ND | ND |
| ALS 1 | High | Moderate | High | Low | High | High | Moderate | Low |
| ALS 2 | Moderate | Moderate | High | High | High | High | Moderate | Moderate |
| ALS 4 | High | High | Moderate | High | High | High | High | High |
| ALS 5 | High | Moderate | High | Low | High | High | High | Low |
| ALS 7 | High | Moderate | High | Low | High | High | Moderate | Low |
| ALS 8 | High | Moderate | High | High | High | High | High | High |
| ALS 9 | Moderate | Low | High | Moderate | High | High | High | Moderate |
| ALS 11 | Moderate | Moderate | Moderate | High | Moderate | High | High | Moderate |
| ALS 12 | Moderate | Moderate | Moderate | Moderate | Moderate | Low | Moderate | Moderate |
| ALS 13 | Moderate | Low | Moderate | Low | Moderate | Low | Moderate | Low |
Immunoreactivity scoring for motor neurons in controls and ALS cases (case numbers are the same as in Table 1 ▶ ). The levels of expression are indicated as low, moderate, and high with ND denoting nondetectable levels of the protein.