Table 2.
Reactivity of the 4F10TT and 4C8MS mAbs with Human Normal Adult Tissues
| Organ | Tissue | mAb | |
|---|---|---|---|
| 4F10 | 4C8 | ||
| Esophagus | Basement membrane | + | − |
| Muscular layer of mucosa | + | − | |
| Muscular layer | + | − | |
| Stomach | Basement membrane | + | ± |
| Muscular layer of mucosa | + | − | |
| Muscular layer | + | − | |
| Intestine | Basement membrane | + | ± |
| Muscular layer of mucosa | + | ± | |
| Muscular layer | + | ± | |
| Liver | Sinusoidal capillaries | + | − |
| Central veins | + | − | |
| Kidney | Medulla | + | + |
| Cortex | + | − | |
| Adrenal gland | Medulla | + | − |
| Cortex | + | − | |
| Pancreas | + | − | |
| Lung | Alveolar wall | + | − |
| Cartilage | Perichondrium | + | − |
| (Trachea) | Chondrocytes | + | − |
| Blood vessel | Muscular artery | + | + |
| Capillary vessel | + | − | |
| Cardiac muscle | − | − | |