Figure 7.

Heparin does not affect apoptosis in myometrial and leiomyoma SMCs. Myometrial (Myo) and leiomyoma (Fib) SMCs were treated with 10% FCS in the presence or absence of 500 μg/ml of heparin (500 H) for 2 days. Staurosporine (0.5 μmol/L) (S) was used as a positive control. The caspase-3 inhibitor DEVD-fmk was used to inhibit the caspase-3 activity induced by staurosporine (S + I). Apoptosis was analyzed using a colorimetric caspase-3 kit. Patients shown are patients B and D from Tables 1 and 2 ▶ .