Table 1.
Effects of STZ-Induced Diabetes on Body Weight and Blood Glucose Levels in Control and Diabetic Rats
| Animals | n | % Weight change | Blood glucose level |
|---|---|---|---|
| Control | 21 | 19.6 ± 0.9 | 118.6 ± 12.12 |
| Diabetic | 21 | −18.8 ± 1.6 | 411.7 ± 15.2* |
| Control+ L-NAME | 12 | 15.6 ± 1.35 | 100.6 ± 9.5 |
| Diabetic+ L-NAME | 12 | −20.6 ± 0.8 | 446.4 ± 21.9* |
| Control+ uric acid | 12 | 15.9 ± 1.2 | 96.5 ± 8.3 |
| Diabetic+ uric acid | 12 | −19.4 ± 1.4 | 468.5 ± 15.47* |
Data are mean ± SE. Animals were made diabetic by a single STZ injection (65 mg/kg) in freshly prepared 1 mmol/L sodium citrate buffer, pH 4.5. Average starting weight of untreated control and diabetic rats was 236 ± 5.95. Average starting weight of L-NAME and uric acid-treated rats was 275 ± 2.1 and 264 ± 9.1, respectively.
*, P < 0.05 compared to corresponding control.