Figure 4.

Identification of genes for biological discovery. The thumbnail panels represent the top 500 genes for each tumor type scored by Student’s t-test analysis and sorted by increasing P value (shown as negative log P value). The second column shows rank according to P value where a higher value corresponds to a lower P value; the first value indicates rank within genes that discriminate the particular tumor subtype; the second value indicates rank within all genes that discriminate any tumor subtype. Light to dark color variation in the left panel represents high to low levels of expression. Annotated genes were selected according to biological interest from the top 500 genes that discriminate any STS subtype. All genes for fibrosarcoma failed to satisfy this criterion. See Supplemental Data at http://www.amjpathol.org for detailed gene lists.