Table 2.
Summary of Data from Proliferation Studies
| Experiment* | Fragments (n) | Epithelial cells,† mean (SD) | Ki-67 labeling index,‡ % (SD) | P | |||
|---|---|---|---|---|---|---|---|
| Anti-β8 | Control | Anti-β8 | Control | Anti-β8 | Control | ||
| 1 | 20 | 20 | 1638 (844) | 1916 (1104) | 38.5 (15.4) | 28.3 (15.1) | <0.05 |
| 2 | 23 | 17 | 973 (483) | 1260 (640) | 43.3 (13.3) | 32.0 (15.4) | <0.05 |
| 3 | 20 | 17 | 905 (724) | 660 (470) | 40.9 (10.9) | 19.2 (13.9) | <0.001 |
| Anti-TGF-β | Control | Anti-TGF-β | Control | Anti-TGF-β | Control | P | |
|---|---|---|---|---|---|---|---|
| 1 | 17 | 16 | 1594 (575) | 1715 (1077) | 30.1 (13.1) | 10.1 (7.1) | <0.001 |
| 2 | 18 | 16 | 647 (318) | 461 (397) | 57.6 (9.6) | 23.0 (10.6) | <0.001 |
| 3 | 18 | 18 | 917 (591) | 682 (436) | 54.7 (11.3) | 14.8 (8.8) | <0.001 |
*Each experiment represents fragments obtained from a different patient.
†Mean number of epithelial cells counted per fragment.
‡Percentage of epithelial cells showing nuclear staining with anti-Ki-67.