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Effect of E-cadherin expression on in vivo MMP production. Immunohistochemistry with monoclonal antibodies directed against human MMP-1 (a and b, respectively), MMP-2 (c and d, respectively), MMP-3 (e and f, respectively), MMP-9 (g and h, respectively), and MT1-MMP (i and j, respectively) was performed to compare the MMP expression profile of E-cadherin- and vector-transfected clones in the in vivo human airway epithelial xenograft model. Bars, 21 μm.
