Table 4.

Pathologic Findings for three Surviving Inhalational Anthrax Patients

Pathology	Patient 2	Patient 8	Patient 9
Duration of antibiotics in relation to specimen collection	11 days for bronchial biopsy, 14 days for pleural biopsy	40 hours	3 days for pleural fluid, 6 days for bronchial biopsy
Skin lesions	None	Chronic erosion on neck*	None
Pleural fluid†	Recurrent, L: >500 cc	Progressive, R: 1,400 cc	R: 500 cc
Pleural tissue samples‡	Inflammation, reactive mesothelium	Inflammation, reactive mesothelium	Inflammation, reactive mesothelium
Gram-positive bacilli	None	None	None
Steiner stain	Non-contributory	Bacilli present	Non-contributory
IHC staining in pleural tissues	Abundant granular antigens, rare bacilli	Abundant bacilli and granular antigens	Abundant granular antigens, rare bacilli
IHC staining in transbronchial biopsy specimen	Rare granular antigens	Not available	Rare granular antigens

*The cutaneous lesion on neck was not temporarily or clinically consistent with cutaneous anthrax.

^†Amount of pleural fluid on right (R) and left (L) pleural cavity.

^‡Pleural tissue samples included cell blocks prepared from pleural fluid and a parietal pleural biopsy specimen.