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Independent Factors of Cancer Progression
| Factor | Cancer progression | P value | |
|---|---|---|---|
| Categories | Hazard ratio* (95% CI) | ||
| Phosphorylated ERK-1/ERK-2 | |||
| H-Score† | 0.03 | ||
| Less than 1 | 1 | ||
| Equal or more than 1 | 4.0 (1.1–13.7) | ||
| Grade | 0.0005 | ||
| 1 or 2 | 1 | ||
| 3 | 12.3 (3.0–50.1) | ||
*, Hazard ratios were determined using a Cox’s proportional-hazard model. CI denotes confidence interval.
†H-score, product of the proportion of positive tumor cells by the intensity of staining with the phosphorylated ERK-1/ERK2 antibody.
