Table 3.
Genotype (n) | TC (μg/adrenal) | FC (μg/adrenal) | EC (μg/adrenal) |
---|---|---|---|
Chow-Fed | |||
LDLr−/− (3) | 104.0 ± 42.7a | 20.3 ± 6.9 | 113.6 ± 35.6a |
LDLr−/−/Apo A–I−/− (2) | 23.8 ± 12.3b | 11.2 ± 3.8 | 12.5 ± 6.4b |
Diet-Fed | |||
LDLr−/− (3) | 97.9 ± 25.9a | 12.5 ± 4.8 | 85.4 ± 21.4a |
LDLr−/−/Apo A–I−/− (4) | 12.2 ± 6.4b | 11.4 ± 8.5 | 1.8 ± 0.2c |
Adrenal total and free cholesterol were determined by GLC as described in Experimental Procedures. All values represent mean ± SD of cholesterol mass per total adrenal as determined in (n) female mice. Lowercase letters indicate significant differences at P < 0.05.