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. 2003 Sep;163(3):1201–1213. doi: 10.1016/S0002-9440(10)63480-3

Table 3.

Adrenal Cholesterol in LDLr−/− and LDLr−/−/Apo A–I−/− Mice Fed Chow or an Atherogenic Diet for 16 weeks

Genotype (n) TC (μg/adrenal) FC (μg/adrenal) EC (μg/adrenal)
Chow-Fed
    LDLr−/− (3) 104.0 ± 42.7a 20.3 ± 6.9 113.6 ± 35.6a
    LDLr−/−/Apo A–I−/− (2) 23.8 ± 12.3b 11.2 ± 3.8 12.5 ± 6.4b
Diet-Fed
    LDLr−/− (3) 97.9 ± 25.9a 12.5 ± 4.8 85.4 ± 21.4a
    LDLr−/−/Apo A–I−/− (4) 12.2 ± 6.4b 11.4 ± 8.5 1.8 ± 0.2c

Adrenal total and free cholesterol were determined by GLC as described in Experimental Procedures. All values represent mean ± SD of cholesterol mass per total adrenal as determined in (n) female mice. Lowercase letters indicate significant differences at P < 0.05.