A: Experimental protocol of adoptive transfer using B6 and SCID mice as indicated. B: Significant proliferative response of the splenic T cells against recombinant α-fodrin (JS-1, 10 μg/ml) were confirmed before the transfer (*P < 0.01, Student’s t-test). Antigen-stimulated blastogenesis was measured in spleen T cells from immunized and non-immunized mice. No proliferative responses were found to lysozyme (5 μg/ml), albumin (5 μg/ml), and OVA (5 μg/ml). Data are expressed as counts per minute ± SD in triplicate. C: Representative histological features of the salivary and lacrimal glands in Ovx+transfer, and Ovx-alone mice (hematoxylin and eosin, magnification, ×120). D: Significant proliferative response of the splenic T cells against recombinant α-fodrin (JS-1, 10 μg/ml) in Ovx+transfer B6 mice was observed (*P < 0.01, Student’s t-test). E: Significant proliferative response of the splenic T cells against recombinant α-fodrin (JS-1, 10 μg/ml) in Ovx+transfer SCID mice was observed (*P < 0.05, Student’s t-test). Data are expressed as counts per minute ± SD in triplicate.