Table 2.

Cytoplasmic and Nuclear Expression of HIF-1α in Ovarian Carcinomas According to FIGO Stage and Histological Type

	Total	Cytoplasmic expression					Nuclear expression
			−	+	++	≧+	%	−	+	%
	76	14	40	22	62/76	82	44	32	42
FIGO stage
I	37	7	16	14	30/37	81	20	17	46
II	10	3	5	2	7/10	70	6	4	40
III	24	3	17	4	21/24	88	15	9	38
IV	5	1	2	2	4/5	80	3	2	40
Histology
Serous	27	5	14	8	22/27	82	16	11	41
Mucinous	7	3	3	1	4/7	57	5	2	29
Endometrioid	17	2	9	6	15/17	88	11	6	35
Clear cell	25	4	14	7	21/25	84	12	13	52

Cytoplasmic immunostaining was estimated as follows: −, 0% positive cells; +, 1–50% positive cells; ++, >50% positive cells.

Nuclear immunostaining was classified as follows: −, absence of tumor cells with nuclear staining; +, presence of tumor cells with nuclear staining.