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a: Plasma cholesterol concentrations of wild-type, LDLR heterozygous knockout (LDLR+/−) and apolipoprotein E homozygous knockout (ApoE−/−) mice with (Tg) or without (C) the eNOS-GFP transgene. *, P < 0.01 versus controls; **, P < 0.001 versus controls. b and c: Fractionation of lipoproteins by gel filtration of plasma from mice with wild-type background (b) or apolipoprotein E knockout background (c). Fraction 1–5 contain VLDL, 6–11 contain LDL, and 12–20 contain HDL.
