. Author manuscript; available in PMC: 2007 May 14.

Published in final edited form as: Biochemistry. 2006 Apr 18;45(15):4808–4818. doi: 10.1021/bi052294c

Table 4.

Conformations of L2 and L4 Loops

loop	E_ox^A177V (pH 6.5)	E_ox^{A177V ·LY} (pH 6.5)	E_ox^WTa (pH 7.4)	E_ox^{E28Q· MTHF a} (pH 7.4)
L4 (Asp120)	open^b	closed^b	open	closed
L2 (Ala62)	closed	open	closed	closed

Previously reported structures (25).

See Figure 7 for description of “open” and “closed”.