Figure 4. Gene and protein domain structure in lengsins.
Gene structure and domain structure in vertebrate lengsins. Gene structure for mammals (M) and non-mammals (NM) is shown with boxes representing exons and numbers in italics indicating the splicing phase of the introns. The domain structure of lengsin is shown schematically with N-terminal, GRASP, GS catalytic and C-terminal domains. The red striped domains constitute the GS homology region. NM shows the gene structure for lengsin in zebrafish and chicken genomes; M shows the structure for mammalian genes. In primates exon 3 is skipped. For both gene structures, the approximate correspondence of exons and protein domains in lengsin are indicated by dotted lines.