. Author manuscript; available in PMC: 2007 May 14.

Published in final edited form as: J Am Chem Soc. 2006 Jul 26;128(29):9302–9303. doi: 10.1021/ja062637

Table 1.

Evaluation of Metal Alkoxides

graphic file with name nihms16459f6.jpg

entry	R–M	result	anti:syn^a
1	MeAlCl₂	no reaction	n.a.
2	n-BuLi	40% of 11^b	n.a.
3	Bu₃La	58% of 11^c	n.a.
4	EtMgBr	71% of 3a^c	6:1
5	EtMgBr	97% of 3a^c,^d	10:1

Determined by ¹H NMR spectroscopy.

¹H NMR yield versus an internal standard.

Isolated yield.

Reaction solvent: 2:1 THF/CH₂Cl₂.