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. Author manuscript; available in PMC: 2008 Jun 1.
Published in final edited form as: Biomaterials. 2007 Feb 9;28(16):2547–2571. doi: 10.1016/j.biomaterials.2007.01.039

Table 5.

Characterization methods using blood components

Blood component Function characterized Result for non-activated EC Combination of molecules dominating response
Recalcified plasma Fibrin generation Long recalcification time TF, TFPI, TM, AT
Platelets Platelet adhesion Platelet activation Low platelet adhesion and spreading and low (serotonin) release Prostacyclin, vWF, NO, PECAM
Leukocytes WBC adhesion WBC activation Low adhesion and activation V-CAM, I-CAM, E-selectin, PECAM
Fibrin dissolution Fibrinolysis Functional EC will lyse clot tPA, PAI-1

AT Antithrombin

TFPI Tissue factor pathway inhibitor

TM Thrombomodulin

TF Tissue factor

NO Nitric oxide

tPA Tissue plasminogen actiator

PAI-1 Plasminogen activator inhibitor type 1