Table 1.

Distribution of bcl-2 and bax Status in 203 Patients with NSCLC According to Clinicopathological Characteristics

Characteristics	n	bcl-2 Status			bax Status			bcl-2/bax Ratio
		Positive	Negative	P value	Positive	Negative	P value	≥1	<1	P value
Smoking
Nonsmoker	57	18	39	0.2379	44	13	0.2963	11	46	0.1397
Smoker	146	61	85		102	44		45	101
Age at surgery (years)
<60	72	29	43	0.8845	55	17	0.3747	20	52	>0.9999
≥60	131	50	81		91	40		36	95
Sex
Male	152	61	91	0.6542	107	45	0.5116	45	107	0.3518
Female	51	18	33		39	12		11	40
Tumor status
T1	53	21	32	0.5735	39	14	0.6347	12	41	0.4037
T2	91	36	55		62	29		26	65
T3	42	18	24		31	11		15	27
T4	17	4	13		14	3		3	14
Nodal status
N0	121	54	67	0.1022	82	39	0.1559	37	84	0.4863
N1	31	12	19		21	10		9	22
N2	43	12	31		36	7		9	34
N3	8	1	7		7	1		1	7
Pathological stage
Stage I	95	39	56	0.1106	65	30	0.0800	25	70	0.0878
Stage II	43	23	20		27	16		18	25
Stage IIIA	41	12	29		33	8		9	32
Stage IIIB	24	5	19		21	3		4	20
Differentiation
Well	36	11	25	0.3140	31	5	0.1950	10	26	0.1195
Moderately	101	38	63		75	26		22	79
Poorly	66	30	36		40	26		24	42
Histology
Adenocarcinoma	121	35	86	0.0016	91	30	0.0231	25	96	0.0273
Squamous cell carcinoma	71	39	32		51	20		27	44
Large-cell carcinoma	11	5	6		4	7		4	7
Total number of patients	203	79	124		146	57		56	147