Table 3.

Five-Year Survival of 203 Patients with NSCLC According to Clinicopathological Characteristics and Gene Status

Characteristics	bcl-2 Status			bax Status			bcl-2/bax Ratio
	Positive	Negative	P value	Positive	Negative	P value	≥1	<1	P value
Smoking
Nonsmoker	79.7	54.7	0.0565	57.5	76.9	0.1597	88.9	56.8	0.0630
Smoker	73.4	43.8	0.0027	57.3	54.9	0.9239	79.5	45.9	0.0014
Age at surgery (years)
<60	74.4	33.6	0.0015	46.4	56.5	0.3590	77.9	38.8	0.0049
≥60	74.7	54.1	0.0610	62.4	61.2	0.8585	83.3	54.2	0.0240
Sex
Male	71.1	45.7	0.0064	55.3	57.9	0.6421	76.2	47.4	0.0041
Female	86.6	51.1	0.0169	60.8	66.7	0.6470	100.0	53.3	0.0241
Tumor status
T1	77.1	65.1	0.2830	74.7	56.2	0.1407	81.5	67.0	0.3775
T2	76.5	46.8	0.0357	56.7	62.8	0.6462	86.5	47.5	0.0063
T3	77.8	31.3	0.0042	44.4	72.7	0.1514	80.0	35.6	0.0086
T4	25.0	28.8	0.5934	35.7	0.0	0.8048	33.3	26.8	0.9101
Nodal status
N0	81.8	65.8	0.1100	74.4	70.0	0.6588	91.1	65.2	0.0233
N1	81.5	37.9	0.0259	57.3	50.0	0.5671	74.1	46.8	0.1692
N2	41.7	15.3	0.3248	21.3	28.6	0.9542	55.6	13.9	0.0691
N3	0.0	0.0	0.8223	14.3	0.0	0.2092	0.0	0.0	0.8223
Pathological stage
Stage I	82.2	70.3	0.4214	78.8	67.7	0.1592	95.0	68.6	0.0881
Stage II	85.6	30.0	0.0004	53.5	68.8	0.5087	80.8	45.5	0.0283
Stage IIIA	50.0	23.5	0.2738	29.5	37.5	0.9136	66.7	21.3	0.0390
Stage IIIB	20.0	23.7	0.9037	28.6	0.0	0.9621	25.0	22.5	0.8673
Differentiation
Well	81.8	67.5	0.4796	69.6	80.0	0.6509	80.0	68.8	0.6211
Moderately	73.2	49.4	0.0107	57.8	61.4	0.4090	83.4	51.5	0.0065
Poorly	73.3	26.9	0.0026	44.5	52.9	0.5095	79.2	30.4	0.0018
Histology
Adenocarcinoma	74.1	43.4	0.0039	53.6	47.7	0.7856	77.5	46.0	0.0131
Squamous cell carcinoma	73.7	55.9	0.1216	62.3	75.0	0.3966	84.4	54.3	0.0162
Large-cell carcinoma	80.0	50.0	0.3674	50.0	71.4	0.4144	75.0	57.1	0.6242
Total number of patients	74.5	46.6	0.0006	56.5	59.8	0.6103	81.0	48.7	0.0004