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. 1999 Sep;155(3):955–965. doi: 10.1016/s0002-9440(10)65195-4

Table 4.

Multivariate Regression Analysis in Predicting Survival of 203 Patients with NSCLC

Histology variables Assigned score NSCLC Adenocarcinoma Squamous cell carcinoma
Hazard ratio (95% CI) P value Hazard ratio (95% CI) P value Hazard ratio (95% CI) P value
bcl-2 Status
Positive 0 0.937 (0.451–1.948) 0.8617 1.475 (0.447–2.870) 0.5232 0.404 (0.131–1.250) 0.1158
Negative 1
bcl-2/bax Ratio status
≥1 0 3.290 (1.360–7.961) 0.0083 3.242 (1.272–8.262) 0.0137 6.610 (1.750–24.966) 0.0053
<1 1
p53 Status
Wild type 0 1.255 (0.805–1.954) 0.3162 1.314 (0.687–2.510) 0.4090 1.767 (0.756–4.129) 0.1884
Mutant 1
Smoking
Nonsmoker 0 0.812 (0.419–1.574) 0.5378 0.749 (0.318–1.764) 0.5083 0.617 (0.149–2.551) 0.5047
Smoker 1
Sex
Male 0 0.496 (0.251–0.979) 0.0431 0.384 (0.169–0.875) 0.0228 1.532 (0.338–6.942) 0.5799
Female 1
Age at surgery (years)
<60 0 1.084 (0.674–1.743) 0.7395 1.364 (0.726–2.565) 0.3349 1.605 (0.577–4.466) 0.3645
≥60 1
Tumor status
T1 1 1.228 (0.956–1.576) 0.1075 1.370 (0.987–1.902) 0.0600 1.108 (0.683–1.798) 0.6771
T2 2
T3 3
T4 4
Nodal status
N0 0 1.914 (1.505–2.434) <0.0001 1.732 (1.290–2.326) 0.0003 3.172 (1.819–5.529) <0.0001
N1 1
N2 2
N3 3
Differentiation
Well 0 1.398 (0.987–1.980) 0.0590 1.869 (1.187–2.942) 0.0069 0.756 (0.374–1.528) 0.4361
Moderately 1
Poorly 2