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Double immunostaining experiments for the simultaneous localization of the Ki-67 antigen (blue reaction product) and β1C (brown reaction product) in two different breast carcinomas exhibiting low (A) and high (B) proliferative fractions. An inverse correlation is documented between the number of neoplastic cells immunoreactive for the Ki-67 antigen and the expression of β1C. Original magnifications: A, ×250; B, ×400.
