Table 2.
Summary of Immunofluorescence Results Obtained with Antibodies to Phospho-CK8 (5B3, LJ4) and to Phospho-CK18 (8250) on Human Control Livers and Human Alcoholic Hepatitis
| 5B3 | LJ4 | 8250 | 3055 | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| P | CK | MB | P | CK | MB | P | CK | MB | P | CK | MB | |
| Hu-Co | ++ | + | 0 | − | − | 0 | + | − | 0 | + | − | 0 |
| Hu-AH | + | ++ | +++ | + | + | +++ | + | + | +++ | + | + | +++ |
The degree of staining was estimated from − (no staining) to +++ according to the intensity and percentage of labeled cells. 0, no MBs present.
Hu-Co, control liver; Hu-AH, alcoholic hepatitis; P, cytokeratin staining at the cell periphery; CK, staining of the whole cytoplasmic cytokeratin IF network; MB, Mallory bodies.