Figure 2.

Expression of laminins in the crypts of control and CD small intestine. Proportions (in percentages) of crypts expressing laminin α1,2, and 3 chains were determined by indirect immunofluorescent staining in control as well as in paired uninflamed (CDU) and inflamed (CDI) CD small intestinal sections by counting a minimum of 100 crypts on each section. Partially stained crypts (see Figure 1b ▶ as an example of minimally labeled crypts) were scored as positive. Six distinct specimens were used as controls, whereas 11 paired specimens were analyzed in the CD group. Asterisks over bars indicate a statistical difference: *, P < 0.05; **, P < 0.01; ***, P < 0.005.