Figure 3.

Expression of laminin α chain transcripts in small intestine from patients with CD. a: Representative RT-PCR analysis of α1, α2, and α3 chain mRNA in uninflamed (U) and corresponding inflamed (I) CD specimens. -RT, RT omitted. S14 transcript was determined to ensure complementary DNA integrity and to compare amounts of starting RNA material in the various samples. b: Amounts of α1, α2, and α3 transcripts in paired uninflamed (U) and inflamed (I) specimens (n = 6) were determined relative to S14. Statistical differences between U and I were noted for α1 (asterisk: P < 0.05).