Table 1.
Characteristics of Participant Groups
Tx Naïve Study | Abstinent Alcoholic Study | Effect Size (%) | |||||
---|---|---|---|---|---|---|---|
Tx Naïve (N=58) | Controls (N=58) | Abs. Alc (N=43) | Controls (N=58) | TxN vs. Controls | Abs. Alcs Vs TxN | Controls Vs Controls | |
Variable | |||||||
Age (years) | 31.1 ± 7.8 | 31.3 ± 7.9 | 46.5 ± 6.6 | 44.6 ± 6.6 | 0.0 | 53.9b | 46.0b |
Years Education | 16.2 ± 1.5 | 16.5 ± 1.8 | 15.7 ± 2.1 | 16.2 ± 1.8 | 0.7 | 2.0 | 0.7 |
| |||||||
Alcohol Use Variables | |||||||
| |||||||
Duration of Active Drinking (mos) | 181.2 ± 95.2 | 132.8 ± 98.3 | 260.6 ± 93.7 | 251.2 ± 130.3 | 5.9a | 15.7b | 19.6b |
Average Lifetime Drinking Dose (std. drinks/mos) | 84.9 ± 43.3 | 6.6 ± 6.3 | 157.8 ± 131.8 | 6.8 ± 7.1 | 64.3a | 14.2*** | 0.2 |
Duration of Peak Drinking (mos) | 55.6 ± 55.1 | 59.3 ± 90.9 | 74.4 ± 73.4 | 121.2 ± 136.8 | 0.0a | 2.6 | 7.3b |
Peak Drinking Dose (std. drinks/mo) | 150.9 ± 113.1 | 14.9 ± 13.6 | 317.4 ± 250.9 | 15.9 ± 18.0 | 41.9a | 17.5*** | 0.1 |
Age First met Criteria for Heavy Use | 21.2 ± 4.9 | N/A | 23.5 ± 6.4 | N/A | N/A | 6.3* | N/A |
Level at First Heavy Use | 135.9 ± 42.4 | N/A | 187.1 ± 117.5 | N/A | N/A | 9.1** | N/A |
| |||||||
Family Drinking Density | |||||||
| |||||||
cFamDD_1 | 0.18 | 0.12 | 0.41 | 0.15 | 2.6 | 14.5*** | 0.7 |
dFamDD_2 | 0.20 | 0.11 | 0.25 | 0.14 | 6.6** | 2.0 | 0.7 |
| |||||||
Deviance Proneness & Externalizing Symptoms | |||||||
| |||||||
CPI Socialization Scale | 31.6 ± 5.4 | 37.2 ± 4.5 | 27.7 ± 5.9 | 37.1 ± 3.7 | 25.4*** | 10.4*** | 0.2 |
MMPI Pd Scale | 18.7 ± 4.5 | 16.1 ± 3.2 | 22.0 ± 4.2 | 16.0 ± 3.6 | 10.8*** | 11.7*** | 0.0 |
eExternalizing Symptoms (#) | 9.8 ± 7.7 | 5.6 ± 5.1 | 14.2 ± 7.4 | 4.7 ± 4.3 | 9.6*** | 9.1** | 0.0 |
| |||||||
Gambling Game | 33.2 ± 31.7 | 38.2 ± 29.2 | 23.1 ± 30.3 | 38.2 ± 28.2 | 0.9 | 2.0 | 0.1 |
Measures are reported mean ± standard deviation. Effect is significance:
p≤0.05,
p≤0.01,
p≤0.001.
Statistical comparisons of the groups on alcohol use variables are not valid since alcohol use was part of the group selection criteria.
Statistical comparisons on age and variables associated with subject’s age are not appropriate since age was associated with the study selection criteria.
Total number of problem drinking 1st degree relatives divided by the total number of1st degree relatives.
Total number of problem drinking 2nd degree relatives divided by the total number of 2nd degree relatives.
Sum of antisocial personality disorder and conduct disorder symptoms from the DIS N/A: Not applicable; mos: months; std. drinks/mo: number of standard drinks per month