Fig. 2.

Lymphocytes from glutamic acid decarboxylase 65 (GAD 65) peptide mix-treated animals exhibit a type 2 phenotype. Supernatants from lymph node proliferation assays showed animals treated with intranasal GAD 65 peptide mix, shown in open bars, had significantly greater interleukin-10 production (a) and diminished interferon-γ production (b) in comparison with peptide-treated animals shown in filled bars. Levels are a mean of three experiments with four to five animals/group/experiment. *P < 0·001; **P < 0·01.