Table 5.

Previously reported significant clinical and/or biological differences between men and women with pSS.

		Significant difference
Reference	Female/male ratio	Clinical	BiologicalM: RF, ANA
Diaz-Lopez et al. [13]	521/28	F: thyroid involvement, carpal tunnel syndrome	F: ANA, anti-60-kDa SSA
Drosos et al. [26]	30/12	F: arthritides, Raynaud's syndrome	F: RF, anti-60-kDa SSA
Molina et al. [27]	69/36	None	None
Anaya et al. [28]	25/13	None	F: ANA, anti-60-kDa SSA
This study	137/11	F: Raynaud's syndrome

F: female, RF: rheumatoid factor, ANA: anti-nuclear antibodies.