Fig. 3.

Effect of acteoside treatment on histological parameters in chronic colitis. Mice with established chronic dextran sulphate sodium (DSS)-induced colitis received either acteoside (600 or 120 µg a day) or phosphate-buffered saline (PBS) (no acteoside) per mouse over 5 days. The data presented are representative for two independent experiments with seven mice per group. Box indicates 25th and 75th percentiles and median. Whiskers indicates 90th and 10th percentiles. *Significantly different from the total histological score of the no-acteoside group (a). Three representative colonic haematoxylin and eosin sections from animals treated with 600 µg acteoside (b), 120 µg acteoside (c) or without acteoside (d) are shown (magnification 100×). From the marked areas, enlarged (three- to fourfold) areas are presented.