Figure 1. Predicted topology of HKα2.
The carboxy-terminus of HKα2 used to screen the mouse kidney cDNA library is represented by a dashed line and extends from the EcoRI site of HKα2 to the stop codon (84 carboxy-terminus amino acids). The bold line between transmembrane M7 and M8 of HKα2 represents the binding site to the β-subunit. N = amino-terminus, C = carboxy-terminus, M1-M10 = predicted transmembrane regions.