Table 1.
Descriptions and definitions of each cell type in the models of stem cell differentiation
| Abbreviation | Model | Descriptions | Definitions |
|---|---|---|---|
| ESC | A | Pluripotent stem cell | C57Bl/6 cell line |
| NSC | A | Adult neural stem cell | *Neurosphere |
| LVB | A | Adult mature neural cell | Lateral ventricles of the brain |
| HSC | A | Long-term hematopoietic stem cell | †Lin- c-Kit+ Sca-1+ CD34- Hoelow |
| BM | A | Non-hematopoietic stem cell | Bone marrow main population |
| ESC | B | Pluripotent stem cell | CCE cell line |
| FNSC | B | Fetal neural stem cell | *†Hoelow from neurosphere |
| FLHSC | B | Fetal liver hematopoietic stem cell | †Lin- AA4.1+ c-Kit+ Sca-1+ |
| FLLCP | B | Fetal liver hematopoietic progenitor cell | †Lin- AA4.1+ c-Kit+ Sca-1- |
| FLMBC | B | Fetal liver mature blood cell | †Lin+ |
| LTHSC | B | Long-term hematopoietic stem cell | †Lin- c-Kit+ Sca-1+Rholow |
| STHSC | B | Short-term hematopoietic stem cell | †Lin-c-Kit+ Sca-1+Rhohigh |
| LCP | B | Hematopoietic progenitor cell | †Lin-c-Kit+ Sca-1- |
| MBC | B | Mature blood cell | †Lin+ |
| CD45 | B | Contain long-term hematopoietic stem cells | †CD45+ c-Kit+ Sca-1+ |
Stem cells and progenitor cells are defined in terms of their surface markers (†by FACS sorting) and/or growth characters (*by selective culture). ESCs in both models A and B were functionally tested. For detailed descriptions and related references, see [54,55].