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. 2007 Mar 16;92(11):3878–3884. doi: 10.1529/biophysj.106.100925

FIGURE 2.

FIGURE 2

3-PGK as a source of ATP. (A) The three-dimensional crystal structure of yeast 3-PGK is outlined in shading, together with the projection of its products Mg-ATP (solid) and 3-phosphoglycerate (hatched), modified from Watson et al. (18). Note that the bulky structure of the enzyme provides a lower limit for the size of the ATP source. (B) A hypothetical cluster of all 3-PGK copies contained in an astrocyte would occupy a sphere of ∼100 nm diameter. The lack of domain generation by either arrangement is discussed in the text.