FIGURE 10.

Changes in Na⁺ influx and efflux in the presence of SAC and/or pH stretch-dependent elements, following stretch, in the quiescent cell. Fluxes are calculated as a function of [Na⁺]_i with [K⁺]_i, [Ca²⁺]_i, [Ca²⁺]_SR, and V_m clamped at their quiescent values of 144.19, 6.508 × 10⁻⁵, 0.6817 mM, and −79.90 mV, respectively. Na⁺ efflux through NaK (bold solid line), Na⁺ influx prestretch (solid line), and Na⁺ influx following 10% stretch in the presence of stretch-dependent NHE & AE (pH, dot-dashed line), stretch-dependent NHE & AE, and SAC (SAC & pH dotted line), and SACs (SAC dashed line). ΔJ_NHE indicates the change in Na⁺ flux caused by the addition of stretch-dependent NHE. ΔJ_SAC indicates the change in Na⁺ flux caused by the addition off SACs.