Figure 2.

Mutation spectrum at Ncam/tk in the FIAU^r and GANC^r clones. Calculation of the number of each mutation type in the spontaneous and x-ray exposed populations was performed by dividing the total FIAU^r or GANC^r frequencies into five frequencies based on the proportion of each mutation type [no LOH (+ + +), complete LOH (− − −), and partial LOH (+ − +), (− − +) or (+ − −)] in each population. The mutation type was based on the loss of heterozygosity of microsatellite markers, D9Mit64, D9Mit22, and D9Mit196.