Table 2.

Mutation spectra from small intestine and thymus of MNU-treated and untreated control and MSH2^−/− animals corrected for clonality

Mutation	Untreated MSH2+/+		MNU-treated MSH2+/+		Untreated MSH2−/−		MNU-treated MSH2−/−
	No.	%	No.	%	No.	%	No.	%
Transitions
G:C −> A:T	16	50	29	74	15	42	31	82
A:T −> G:C	4	13	0	0	9	25	0	0
Transversions	9	28	7	18	6	17	1	3
Deletions	1	3	0	0	1	3	2	5
Frameshifts	2	6	3	8	5	14	4	11
Total	32	100	39	100	36	100	38	100