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Treatment-induced changes in LT in total body CD4+ T cells and naive CD45RA+ cells, were determined as described in this report. Total CD4+ T cell body counts were calculated by extrapolation as described; this number times the percentage of RA+ cells equals the total CD45RA+ CD4+ T cell count. The fractions of Ki67+ and TUNEL+ CD4+ T cells in tonsillar biopsies were determined as described in this report, before and at designated times after treatment.
