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γδ T cells are required for VSV-neutralizing IgG responses in αβ T cell-deficient mice. (A) TCRα−/− mice were treated i.p. with monoclonal antibodies against Thy1.2 on days 3 and 1 before immunization with 2 × 106 pfu of live VSV i.v. Antibody treatment was repeated on days 5 and 11. (B) TCRβ−/−δ−/− mice were immunized with 2 × 106 pfu of live or UV-inactivated VSV i.v. One of three similar experiments is shown.
