Figure 10.

(A) Morris water maze platform crossings in trained and untrained quadrants during session 4 (probe trial) in mice aged 4 (n = 21), 12 (n = 26), and 18 (n = 28) months. In the Morris water maze probe trials, all mice crossed the area in the platform trained quadrant more times than they crossed the same area in untrained adjacent and opposite quadrants. (B) Morris water maze time spent swimming in trained and untrained quadrants during session 4 (probe trial) in mice aged 4 (n = 21), 12 (n = 26), and 18 (n = 28) months. Mice generally spent more time swimming in the trained platform quadrant than they did swimming in the untrained adjacent and opposite quadrants.