Table 4.
Marker | Thymoma Type | |||||
A | AB | B1 | B2 | B3 | MNT | |
CD57 | S | S | S | S | S | S |
CD3 | S | + | + | + | + | + |
CD5 | S | + | + | + | + | + |
CD20 | - | + | + | -/+ | -/+ | +* |
CD1a | - | + | + | + | + | + |
CD99 | - | + | + | + | + | + |
Ki67/MIB1 | <10% | >80% | >80% | >80% | >80% | >80% |
MNT = multinodular thymoma
-/+ = variably (large numbers of intratumoral CD20+ lymphocytes in type B2 (n = 1) and type B3 (n = 3) thymomas associated with autoimmune disorder)
* = numerous large stromal CD20+ lymphoid aggregates
S = single cells