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Change in the volume of normal-appearing white matter (NAWM) projected by the model in healthy control subjects (HC) and patients treated for medulloblastoma (MB) without ventricular shunts starting at the age of 6 years (A) or 12 years (B). A solid line at zero change is shown for reference. Absolute volume is standardized to the intercept at ages 6 and 12 to facilitate comparison. The curves were generated by using quadratic regression models.
