Table 1.
Chemotherapy regimens used to treat 38 of the 52 patients in this study
| Protocol | N | Description* |
|---|---|---|
| CNS8 | 8 | Carbo/VP-16 + Cyclo/VCR (post-RT for patients with PD) |
| CNS14 | 1 | Carbo/Cyclo/VP-16 (pre-RT) |
| P9031 | 10 | CDDP/VP-16 (± pre-RT) + Cyclo/VCR (post-RT) |
| PACKER | 1 | CCNU/CDDP/VCR (post-RT) |
| CCSG921 | 1 | “8-in-1” (Zeltzer et al., 1999) |
| SJMB96 | 17 | Topotecan (pre-RT), Cyclo/CDDP/VCR (post-RT) |
*
Abbreviations: Carbo, carboplatin; CCNU, lomustine; CDDP, cisplatin; Cyclo, cyclophosphamide; PD, progressive disease; RT, radiation treatment; VCR, vincristine; VP-16, etoposide.