Table 2.
Grade** | |||||||
---|---|---|---|---|---|---|---|
Toxicity | 1 | 2 | 3 | 4 | 5 | Total | % Points |
Flu-like symptoms | |||||||
Fever | 1 | 1 | (5.6) | ||||
Fatigue | 4 | 2 | 6 | (33.3) | |||
Rigors, chills | 1 | 1 | (5.6) | ||||
Gastrointestinal | |||||||
Anorexia | 1 | 2 | 3 | (16.7) | |||
Diarrhea | 1 | 1 | (5.6) | ||||
Dyspepsia/heartburn | 1 | 1 | (5.6) | ||||
Nausea | 3 | 2 | 5 | (27.8) | |||
Vomiting | 1 | 1 | (5.6) | ||||
Renal | |||||||
Urine frequency/urgency | 1 | 1 | (5.6) | ||||
Neurology | |||||||
Confusion | 1 | 1 | 2 | (11.1) | |||
Neuropathy-cranial | 1 | 1 | (5.6) | ||||
Speech impairment | 1 | 1 | (5.6) | ||||
Memory loss | 1 | 1 | (5.6) | ||||
Neuropathy-motor | 1 | 1 | 2 | (11.1) | |||
Seizure(s) | 1 | 1 | (5.6) | ||||
Depressed conscious | 2 | 2 | (11.1) | ||||
Tremor | 2 | 2 | (11.1) | ||||
Pain | |||||||
Headache | 1 | 2 | 3 | (16.7) | |||
Pulmonary | |||||||
Dyspnea | 1 | 1 | (5.6) | ||||
Dermatology | |||||||
Alopecia | 2 | 2 | (11.1) | ||||
Injection site reaction | 1 | 1 | (5.6) | ||||
Pruritus | 1 | 1 | (5.6) | ||||
Rash/desquamation | 1 | 1 | (5.6) | ||||
Any | 9 | 10 | 4 | 0 | 0 | 12 | (66.7) |
Considered by investigator to be possibly, probably, or definitely related to protocol treatment.
Toxicity graded according to National Cancer Institute Common Toxicity Criteria version 2.0.