Fig. 2.

Immunohistochemical analyses of normal brain and astrocytoma tissue demonstrate tumor-specific expression of RPTPβ. (A) Sections from normal brain (a–d), glioblastoma (e–g), and astrocytoma grade III tissue (h) were stained with RPTPβ carboxyl-terminus antibody (brown DAB chromagen) and counterstained with hemotoxylin (blue). Representative samples of normal brain sections (including cerebellum [c] and RPTPβ -positive glioblastoma tumors) are shown here. (B) Glioblastoma tissue sections. Of the 24 glioblastoma tissues tested in this matched set of sections, only one had significant stain for long RPTPβ (left panel) but did not stain for short RPTPβ (right panel).