Table 1.

TCHA patients with pineal region germinoma Pt age

Pt	Age at dx	Sex	Preoperative symptoms	Preoperative MRI	Surgery	Intraoperative findings	Post-chemo MRI	Post-XRT MRI	Post-treatment symptoms/most recent MRI	Follow-up (months)
1	21	M	HA, N/V, Parinaud’s	1) Pineal lesion		Clean 3rd vent floor	CR	CCR	Partial Parinaud’s	27
				2) 3rd vent floor clear	Biopsy*		No
				3) HCP	ETV		HCP		CCR
2	11	M	DI	1) Pineal lesion		Tumor bulging through Monro	CR	CCR	DI	21
				2) Suprasellar lesion	Biopsy		No		CCR
				3) No HCP			HCP
3	12	F	HA, N/V, DI	1) Pineal lesion		Tumor studding on floor of 3rd vent	CR	CCR	DI	36
				2) Enhancing 3rd vent floor	Biopsy		No		CCR
				3) HCP	ETV		HCP
4	12	F	N/V, Hemiparesis, DI	1) Pineal lesion		Tumor studding on floor of 3rd vent	PR	CR	Improved hemiparesis	44
				2) BG lesion	Biopsy		No
				3) HCP	ETV		HCP		DI CCR
5	21	M	HA, ataxia, LOC, DI	1) Pineal lesion		Tumor studding on floor of 3rd vent	PR	CR	DI	59
				2) Enhancing 3rd	Biopsy		No		CCR
				vent floor, suprasellar	ETV		HCP
				Region
				3) HCP
6	14	M	Diplopia, HA, DI	1) Pineal lesion		Tumor studding on floor of 3rd vent	CR	CCR	DI	47
				2) 3rd vent floor clear	Biopsy				No
				3) HCP	ETV
7	14	M	HA, N/V, DI	1) Pineal lesion		Tumor studding on floor of 3rd vent	CR	CCR	DI	19
				2) Mass on 3rd vent floor	Biopsy		No		CCR
				3) HCP	ETV		HCP
8	16	M	HA, N/V, Diplopia	1) Pineal lesion		Clean 3rd vent floor	CR	CCR	No symptoms	15
				2) 3rd vent floor clear	Biopsy				CCR
				3) HCP	ETV

^*Biopsy indicates endoscopic tumor biopsy.

Abbreviations used: BG, basal ganglia; CCR, continued complete response; CR, complete response; DI, diabetes insipidus; dx, diagnosis; ETV, endoscopic third ventriculostomy; F, female; HA, headache; HCP, hydrocephalus; LOC, loss of consciousness; M, male; N/V, nausea and vomiting; PR, partial response; Pt, patient; 3rd vent, third ventricle.