Table 1.
Progeny of FVLeiden/PZ matings
| Mating pairs | Observed (%) | Expected, % | P* |
|---|---|---|---|
| FV(λ/λ)/PZ(+/−) × FV(λ/λ)/PZ(+/−) | |||
| At 6 weeks | |||
| FV(λ/λ)/PZ(+/+) | 40 (52) | 25 | |
| FV(λ/λ)/PZ(+/−) | 37 (48) | 50 | <0.01 |
| FV(λ/λ)/PZ(−/−) | 0 (0) | 25 | <0.01 |
| At E17.5–E18.5† | |||
| FV(λ/λ)/PZ(+/+) | 7 (21) | 25 | |
| FV(λ/λ)/PZ(+/−) | 18 (53) | 50 | |
| FV(λ/λ)/PZ(−/−) | 9 (26) | 25 | |
| FV(λ/λ)/PZ(+/−) × FV(+/+)/PZ(−/−) (6 weeks) | |||
| FV(λ/+)/PZ(+/−) | 28 (74) | 50 | |
| FV(λ/+)/PZ(−/−) | 10 (26) | 50 | <0.01 |
| FV(λ/λ)/PZ(−/−)‡ × FV(λ/λ)/PZ(+/−) (6 weeks) | |||
| FV(λ/λ)/PZ(+/−) | 16 (100) | 50 | |
| FV(λ/λ)/PZ(−/−) | 0 (0) | 50 | <0.01 |
*
Difference between observed and expected frequencies derived by the confidence interval for binomial distributions.
†
En, embryonic day n.
‡
Single FV(λ/λ)/PZ(−/−) male, derived from a F(λ/+)/PZ(+/−) intercross, mated with five females.