TABLE 1.
Human and murine TNF-α levels in human colonic xenografts infected with E. histolytica
| Samplea source | Mean TNF-α level (pg/ml) ± SDb
|
|
|---|---|---|
| Human | Murine | |
| Untreated mice | 68 ± 50 | 194 ± 163 |
| Anti-TNF-α- + IL-1ra-treated mice | 28 ± 35 | 80 ± 66 |
a
E. histolytica-infected human colonic xenograft tissue samples were collected from groups of 10 untreated or TNF-α- and IL-1ra-treated SCID-HU-INT mice.
b
The values for human TNF-α differed between untreated and anti-TNF-α- and IL-1ra-treated SCID-HU-INT mice at P = 0.08. The values for murine TNF-α differed between untreated and anti-TNF-α- and IL-1ra-treated SCID-HU-INT mice at P ≤ 0.05.