FIG. 2.

Course of parasitemia and survival in A/J mice immunized s.c. with antigen (Ag) alone, antigen in alum, antigen plus IL-12, or antigen plus IL-12 in alum and boosted 3 weeks later by i.p. injection with antigen. Two weeks later, immunized and untreated control mice were challenged i.p. with 10⁶ P. chabaudi AS PRBC. The percentage of PRBC in peripheral blood (A and B) was determined for each group of 5 mice. Data from one of two replicate experiments are presented. Mice were examined twice daily for the duration of the experiment for survival (C). Cumulative data from 6 experiments are presented.