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. 2003 Sep;71(9):4857–4861. doi: 10.1128/IAI.71.9.4857-4861.2003

FIG. 1.

FIG. 1.

Antibody isotype profile of mice inoculated with pcDNA-SOD or pcDNA3. Mice (five per group) were inoculated intramuscularly with 100 μg of pcDNA-SOD or pcDNA3. Sixty days after immunization, serum was collected and antibody titers (shown on the y axis) were evaluated by ELISA. Data are representative of two separate experiments. Each bar represents the mean titer ± SD (error bars) of antibodies in five animals. *, significantly different from titer of IgG1 in mice immunized with pcDNA-SOD (P < 0.003).